Member Updates

Member Updates

When it comes to important topics at the forefront of heart disease research and education, Sarver Heart Center faculty are there. This was evidenced by significant involvement in the American Heart Association’s Scientific Sessions 2015, held in Orlando, Fla., during early November.

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The Mechanical Circulatory Support team (from l to r): Jennifer Cook, MD, Richard Smith and Edward Betterton  lead an interactive simulation session at the American Heart Association Scientific Sessions 2015.

Mechanical Circulatory Support Simulation, a first-of-its-kind educational tool that premiered at the AHA Scientific Sessions, was developed by Jennifer Cook, MD, Richard Smith, and Edward Betterton. Dr. Cook is an Associate Professor of Medicine at the UA Sarver Heart Center and a member of the AHA educational planning committee; Smith is technical director, and Betterton is clinical engineer in the Artificial Heart Program at Banner University Medical Center - Tucson.

The simulation gave physicians an opportunity to discuss complicated cases while exposed to real-time observation and hemodynamic feedback using a unique simulator developed at the University of Arizona.  “These sessions allowed physicians to make decisions in complex patients and get immediate feedback about the results, a practical experience with pharmacological and mechanical treatment choices never before offered, and very valuable to practicing physicians and trainees attending the meeting,” said Dr. Cook, who directs the Mechanical Circulatory Support Program at Banner – University Medical Center Tucson. She moderated several panels of experts leading interactive discussions of complex heart failure patient scenarios, which included cardiogenic shock and left ventricular assist devices. Marvin Slepian, MD, Professor of Medicine and Biomedical Engineering at the UA and Director of the Arizona Center for Accelerated Biomedical Innovation was a panelist.

Nancy Sweitzer, MD, PhD, director of the UA Sarver Heart was awarded an American Heart Association Cardiovascular Genome-Phenome Study (CVGPS) Discovery Grant. The grant program is part of the newly formed AHA Institute for Precision Cardiovascular Medicine. CVGPS combines the power of long-term population studies with the precision of molecular analysis to unravel key distinctions between and within subgroups of patients.

“The Institute is working to create advances in precision cardiovascular care which to this point have been absent at the bedside. AHA’s goal is to provide small seed grants that will encourage other organizations to take up the challenging initiative of precision medicine, which is an area of focus at the UA Health Sciences,” said Dr. Sweitzer, who is a member of the American Heart Association’s Heart Failure and Transplant Committee.

The research project is titled, “Large-Scale Discovery of Mechanistic and Predictive Biomarkers in Phenotypically Distinct Groups of Patients with Heart Failure and Preserved Ejection Fraction.”

Karl B. Kern, MD, co-director of the UA Sarver Heart Center and Professor of Medicine, began his term as vice chair of the American Heart Association’s Emergency Cardiovascular Care Committee. This national committee is charged with writing and producing the CPR guidelines and follow-up educational materials. It also oversees science, system of care and educational subcommittees, and interfaces with the International Liaison Committee for Resuscitation.

Julia Indik, MD, PhD, moderated a poster session on “Treatment of Arrhythmias: Outcomes of Ablation of Atrial Fibrillation.” She also served as a judge on the selection committee for the Cournand and Comroe Award, sponsored by the Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation (3CPR), to recognize the research accomplishments of young investigators. She also was thanked by The American College of Cardiology (ACC) and American Heart Association (AHA) for her role in writing the 2015 Guideline for the Management of Adult Patients with Supraventricular Tachycardia.

Beyond the AHA

http://www.iplantcollaborative.org/sites/default/files/Parker%20Antin_4x6_Crop1.jpgParker Antin, PhD, was elected president of the Federation of American Societies for Experimental Biology Board of Directors. FASEB serves as the largest non-profit organization of U.S. societies dedicated to biological and medical research. The umbrella organization includes 27 societies and 125,000 members whose main goal is to provide a voice in policy for researchers across the country.

Dr. Antin, Professor of Cellular and Molecular Medicine and Associate Dean of Research for the College of Agriculture and Life Sciences, hopes that as FASEB president he will further the dialogue between researchers and policy makers, allowing for advancements in the medical field. Among his concerns, Dr. Antin hopes to improve the crisis in funding, which has experienced a 25 percent drop in inflation-adjusted dollars since 2004.

“This has had a devastating effect in the world of biomedical research, leaving excellent science unfunded, driving young people into other more predictable careers and creating barriers to development of treatments for many diseases including heart disease,” said Dr. Antin. Through improved funding, he hopes that more support will be available for education of graduates and to support the careers of young scientists, reversing the trend of decline in choice of scientific research as a career in the U.S.

Marvin Slepian, MD, (left) was inducted in October as president of the International Society for Mechanical Circulatory Support during its 23rd Annual Meeting in Dubrovnik, Croatia. Also pictured: Uli Steinsiefer (center) – immediate past president and professor of biomedical engineering, Helmholz Institute, University of Aachen; Mark Slaughter MD (right) – past president and professor and chief of cardiothoracic surgery, University of Louisville.

Two projects from Dr. Slepian’s research lab were featured in national publications recently.

The National Institute of Biomedical Imaging and Bioengineering News Room highlighted Dr. Slepian’s research that sheds light on platelet properties and the relationship between ventricular assist devices (VADs) and stroke. Although VAD design has improved and unwanted blood clots occur less frequently,  patients with these devices still experience unacceptably high risk of both bleeding and stroke. The Slepian lab has focused on changing platelet properties to reduce risk of platelet activation and dangerous clotting.

About 5.1 million people in the United States have heart failure and an estimated 75,000 to 150,000 patients with end-stage heart failure are implanted with VADs, according to the American Heart Association. While ventricular assist device therapy was initially used to “bridge” patients with advanced heart disease to transplant, it is now approved as a “destination” therapy based on the profound improvement in quality of life and the increased life expectancy patients experience with this therapy.

Science Advances published an article on the Slepian lab’s work on stretchable, wearable electronic polymers. This technology could be used to design adhesive skin patches which could monitor blood circulation and help assess patients with blocked arteries, impaired circulation due to diabetes, peripheral vascular disease or other conditions where impaired blood flow can lead to skin breakdown, impair wound healing, or cause organ damage.

Other Recognitions

The Heart Series, a program developed by Charles Katzenberg, MD, Professor of Clinical Medicine, at the UA Sarver Heart Center, and Edna Silva, RN, cardiac rehabilitation nurse and Tai Chi master, received the “Achievement in Wellness Programs” award from Tucson Local Media’s Influential Health and Medical Leaders Awards. The Heart Series is an intensive education program offered twice a year in Tucson, focused on heart disease prevention and health promotion. For more information or to register for the program, visit heartseries.org.

Joseph Alpert, MD, Professor of Medicine, received the “Internal Medicine Excellence in Teaching Award” from the Department of Medicine at the UA College of Medicine – Tucson.

The 2015 graduating fellows from the UA Sarver Heart Center honored Mark Friedman, MD, Clinical Professor of Medicine, with the “Outstanding Faculty Award for the Interventional Cardiology Fellowship Program,” and Prakash Suryanarayana, MD, Assistant Professor of Clinical Medicine (pictured with award), with the “Outstanding Faculty Award for the Cardiovascular Disease Fellowship Program.”

 

 

It was 30 years ago when then-University Medical Center staff teamed up with University of Arizona faculty physicians and scientists to be the first in the world to successfully use the total artificial heart as a bridge to transplant. In celebration of this milestone, 30-year veterans of this pioneering team (including Joan Wild, Peggy Wiggins and Rich Smith, pictured) gathered with colleagues from the Mechanical Circulatory Support Program in September.