Hendrikus (Henk) Granzier, PhD

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Professor of Physiology, Cellular and Molecular Medicine, Biomedical Engineering, Molecular and Cellular Biology, Physiolofical Sciences
Allan & Alfie Norville Endowed Chair for Heart Disease in Women Research
BIO5 Institute
(520) 626-3641

Hendrikus Granzier, PhD, studies the mechanisms whereby the giant filamentous protein titin (the largest protein known) influence muscle structure and function. His lab has shown that titin functions as a molecular spring that mediates acute responses to changing pathophysiological states of the heart. They also study the role of titin in cardiac disease, using mouse models with specific modifications in the titin gene, including deciphering the mechanisms that are responsible for gender differences in diastolic dysfunction. An additional focus of Dr. Granzier’s lab is on nebulin, a major muscle protein that causes a severe skeletal muscle disease in humans. Based on previous work, they hypothesize that nebulin is a determinant of calcium sensitivity of contractile force. To test this and other concepts, he uses a nebulin knockout approach in the mouse. Research is multi-faceted and uses cutting-edge techniques at levels ranging across the single molecule, single cell, muscle, and the intact heart. His research group is diverse and has brought together individuals from several continents with expertise ranging from physics and chemistry to cell biology and physiology.


Robert W. Gore, PhD

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Professor of Physiology/Anatomy
(520) 626-6569

Scott Going, PhD

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Professor of Nutritional Sciences; Research Director, Center for Physical Activity and Nutrition
(520) 621-4705

Arthur F. Gmitro, PhD

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Professor of Radiology & Optical Sciences
(520) 626-4720

Janet Funk, MD

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Research Associate Professor of Medicine
(520) 626-3242

Melissa Faulkner, DSN, RN

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The Gladys E Sorensen Endowed Professor (College of Nursing)
(520) 626-4970

Jose EkVitorin, MD, PhD

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Research Assistant Professor of Physiology
(520) 626-6740

Thomas Doetschman, PhD

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Professor of Cell Biology & Anatomy, BIO5 Institute
(520) 626-4901

Behrooz Dehdashti, PhD

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Research Specialist, Cardiology
(520) 626-1850

Zoe Cohen, PhD

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Assistant Professor, Department of Physiology
(520) 621-5485
  • Ph.D. Physiology
    • University of Arizona, Tucson, Arizona, USA
    • Mechanisms of Platelet Activation in Type 2 Diabetes
  • M.S. Exercise Physiology
    • University of Colorado, Boulder, Colorado, United States
Work Experience
  • Assistant Professor (Educator Scholar Tract), University of Arizona, Tucson, Arizona (2015 - Ongoing)
  • Senior Lecturer, University of Arizona, Tucson, Arizona (2013 - 2015)
  • Lecturer, University of Arizona, Tucson, Arizona (2007 - 2013)
  • AAU STEM Undergraduate Teaching Excellence Award
    • Association of American Universities, Fall 2016
  • Physiology Professor of the Year
    • Physiology Club, Spring 2016
    • Physiology Club, Spring 2015


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