The Sarver Heart Center and the Molecular Cardiovascular Research Program bring together leading investigators studying the biological, molecular, and clinical mechanisms of cardiovascular disease. These laboratories span basic discovery, translational science, and clinical innovation aimed at improving the prevention and treatment of heart disease.
Ardehali Lab
Studies iron metabolism and mitochondrial glucose regulation to uncover mechanisms of heart failure, aging, and cellular stress.
Chorba Lab
Studies cholesterol metabolism and LDL receptor regulation to develop new therapeutics and AI-enabled diagnostics for cardiometabolic disease.
Goldman Lab
Develops regenerative therapies for heart failure using stem-cell–derived cardiomyocytes and engineered heart tissue.
Liang Lab
Integrates genomics, regulatory RNA, and cellular metabolism to understand hypertension and cardiovascular and kidney disease.
Romanoski Lab
Studies how DNA sequence and gene regulation shape endothelial cell biology and contribute to diseases such as atherosclerosis and hypertension.
Sadek Lab
Investigates cardiomyocyte regeneration and molecular pathways that could enable the heart to repair itself after injury.
Szweda Lab
Studies how diet and aging alter cardiac and mitochondrial metabolism, redox balance, and insulin resistance in cardiovascular disease.
Molecular Cardiovascular Research Program (MCRP)
The Molecular Cardiovascular Research Program (MCRP) at the University of Arizona brings together investigators studying the molecular, genetic, and biophysical mechanisms that drive cardiovascular disease. Through interdisciplinary collaboration, the program integrates basic science, translational research, and advanced technologies to understand heart and muscle biology and to develop new therapies for cardiovascular disorders.