Dr. Methawasin graduated from Medical School in Thailand, her home country, where she specialized in cardiac anesthesia. Although she had a stable career she wanted to contribute more through scientific research and decided to come to the United States to earn a PhD in cardiac physiology from the University of Arizona. She joined Dr. Granzier’s laboratory where she has been working as a Research Assistant Professor. She wishes to contribute in important ways to basic research with high clinical significance.
Dr. Methawasin's research seeks to understand pathophysiology of heart failure with preserved ejection fraction (HFpEF) and identify its possible therapeutic targets by using an integrative approach. She is experienced in cardiomyocyte mechanics as well as in-vivo cardiac functional techniques. Her current work focuses on multiple diastolic contributors: titin, microtubular networks, and residual crossbridges, as an integrated system, and to study the progression of diastolic dysfunction in the aged heart at the single cell level.