The inaugural Cardiovascular Research Symposium hosted by the the Sarver Heart Center and Division of Cardiology in the University of Arizona College of Medicine – Tucson’s Department of Medicine, Feb. 3-4, resulted in excellent turnout, great presentations and dynamic dialogue, according to organizers. Over 120 researchers, clinicians, and trainees participated. See a mini-photo gallery from the event below.
The keynote speaker Eric Olsen, PhD, gave an inspiring talk at the HSIB Forum on the U of A Health Sciences campus on “Muscle Making and Muscle Breaking: From Developmental Mechanisms to Therapies for Heart and Muscle Disease.”
Dr. Olsen is the founding chair of the Department of Molecular Biology at UT Southwestern Medical Center in Dallas, where he holds the Annie and Willie Nelson Professorship in Stem Cell Research, Pogue Distinguished Chair in Research on Cardiac Birth Defects and Robert A. Welch Distinguished Chair in Science.
After a short travel break, everyone reconvened at Lowes Ventana Canyon Resort for the afternoon program, where they were greeted with opening comments by U of A Cardiology division chief and Sarver director Hesham Sadek, MD, PhD.
Eight of 18 presenters there were from UTSW, where Dr. Sadek served before joining the College of Medicine – Tucson faculty in early May 2024. Eight were from the U of A and one each came from the University of Wisconsin’s Stem Cell & Regenerative Medicine Center (Ahmed Mahmoud, PhD) and the Centro Nacional de Investigaciones Cardiovasculares’ Cardiovascular Regeneration Program (Miguel Torres, PhD) in Madrid – and where Dr. Sadek is a visiting scientist.
Among presentations from the University of Arizona were:
- Department of Medicine chair James K. Liao, MD, cardiovascular disease specialist, Sarver member and the Robert S. and Irene Flinn Endowed Chair in Medicine – “Rho-associated Kinase (ROCK) as a Therapeutic Target for Fibrotic Diseases”
- Jil Tardiff, MD, PhD, the Steven M. Gootter Endowed Chair for Prevention of Sudden Cardiac Death, professor of cardiology and cellular and molecular medicine, and Sarver and BIO5 Institute member – “Targeting the Cardiac Sarcomere to Modulate Pathogenic Remodeling in HCM & DCM: Structural and Kinetic Approaches”
- Dr. Sadek – “Heart Regeneration: Edging Toward the Clinic”
- Sarver associate director, chair, Department of Cellular & Molecular Medicine, and the Humberto and Czarina Lopez Endowed Chair for Excellence in Cardiovascular Research Sakthivel Sadayappan, PhD – “Myosin S2 and cMyBP-C interactions in Hypertrophic Cardiomyopathy”
- U of A Cardiology professor Luke Szweda, PhD – “Daily Rhythms in Cardiac Metabolism: Tuning in for a Healthy Heart”
- U of A Cardiology professor and program director, Interventional Cardiology Fellowship, Deepak Acharya, MD, MSPH – “Novel Therapies for Heart Failure.”
All of the talks are available via Sarver Heart Center Ground Rounds archived on the U of A Health Sciences BioCommunications streaming website, although a password is required to view them. Contact Sarver outreach and education manager Cara Deery for that: caradeery@arizona.edu.
Sadayappan said the symposium, held in close collaboration with UTSW, provided a platform for exchange of groundbreaking ideas, cutting-edge presentations and dynamic discussions that showcased the remarkable progress in both cardiovascular research and clinical practice.
“I particularly enjoyed engaging with colleagues from UT Southwestern and learning from their insightful presentations. The ample time allocated for Q&A and interactions fostered meaningful dialogue, and the poster sessions were a true highlight. Overall, this first symposium was a tremendous success, setting the stage for continued collaboration and innovation in the field,” Sadayappan added.
The finalists for abstracts and posters presented at the symposium were:
- Graduate Student | Rebecca Slepian, MBA – a second-year medical student at the College of Medicine – Tucson
- Postdoctoral Student | Marjan Aghajani, PhD – a 2024 BIO5 Postdoctoral Fellowship fellow working with Shirin Doroudgar, PhD, Department of Internal Medicine, College of Medicine – Phoenix
- Junior Faculty (basic) | Nikola Sladjevic, MD, PhD – assistant research professor, Division of Cardiology, Department of Medicine, College of Medicine – Tucson, and Sarver Heart Center
- Junior Faculty (clinical) | Kamaldeep Singh, MD – assistant clinical professor, Division of Inpatient Medicine, Department of Medicine, College of Medicine – Tucson
Dr. Singh also won the prize for Best Overall Abstract, presenting on another topic, “Percutaneous Coronary Intervention Reduces Mortality Compared to Conservative Therapy in Elderly Patients Presenting with NSTEMI.” NSTEMI is a type of heart attack where partial blockage of a coronary artery reduces blood flow to the heart muscle, damaging it. Dr. Singh’s research was co-authored by Division of Cardiology fellows Alvaro Altamirano Ufion, MD, Khurram Butt, MD, and Jacob Klewer, MD, in collaboration with faculty members Mathew D. Hutchinson, MD, and Julia H. Indik, MD, PhD.
“This was a wonderful scientific symposium that highlighted cardiovascular care and cutting-edge discovery, while increasing the exposure of the Sarver Heart Center to other academic centers. My appreciation to Dr. Sadek and Dr. Sadayappan for organizing this annual event, and setting the tradition,” said Dr. Liao.
MINI-PHOTO GALLERY *
* Click on images to enlarge. Rollover image with mouse for captions.
(Photos courtesy of Sarver Heart Center and BioCommunications, U of A Health Sciences)
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